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New hope for tough leukemia: 3-Drug attack launched

NCT ID NCT07311746

First seen Jan 11, 2026 · Last updated Apr 29, 2026 · Updated 14 times

Summary

This study tests whether a combination of three drugs (cladribine, ruxolitinib, and venetoclax) can control a rare and aggressive blood cancer called T-cell prolymphocytic leukemia (T-PLL) that has returned or not responded to prior therapy. About 36 adults will receive the drug combo, and researchers will monitor side effects and how well the disease responds. The goal is disease control, not a cure, as ongoing management is expected.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The University of Texas M. D. Anderson Cancer Center

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

Explore the condition pages connected to this study.