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Joint infection diagnosis: new test matches up against standard guidelines

NCT ID NCT06153446

First seen Nov 01, 2025

Summary

This study looked at a new test called Synovasure that checks joint fluid for signs of infection after hip or knee replacement. Researchers compared its accuracy to current clinical guidelines using 810 stored samples. The goal was to see if the new test agrees with standard methods for diagnosing periprosthetic joint infection.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Rothman Orthopedic Institute

    Philadelphia, Pennsylvania, 19107, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Synovasure Comprehensive Infection Panel (diagnostic test on synovial fluid)

What this could lead to

If accurate, this test could help doctors diagnose joint infections faster and more reliably after hip or knee replacement.

What could go wrong

This is a completed study using stored samples, not a real-time trial. The test's real-world benefit depends on how it performs in everyday clinical practice.

Conditions

The condition(s) this trial relates to.

juvenile polyposis syndrome periprosthetic joint infection

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.