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New hope for men with hard-to-treat prostate cancer? drug combo enters trial.

NCT ID NCT06228053

First seen Jan 06, 2026 · Last updated Apr 30, 2026 · Updated 14 times

Summary

This study tests a combination of two drugs, SX-682 and enzalutamide, in 53 men with metastatic castration-resistant prostate cancer that has stopped responding to standard hormone therapies. The goal is to see if the combo can shrink tumors, lower PSA levels, or keep the disease stable for at least 6 months. Participants will be monitored for side effects and how long they live without the cancer getting worse.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Duke University

    RECRUITING

    Durham, North Carolina, 27710, United States

    Contact

    Contact Email: •••••@•••••

  • University of California, Los Angeles

    RECRUITING

    Los Angeles, California, 90095, United States

    Contact

    Contact Email: •••••@•••••

  • University of California, San Francisco

    RECRUITING

    San Francisco, California, 94143, United States

    Contact Email: •••••@•••••

    Contact

    Contact Email: •••••@•••••

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact Email: •••••@•••••

    Contact

  • University of Minnesota

    NOT_YET_RECRUITING

    Minneapolis, Minnesota, 55455, United States

    Contact Email: •••••@•••••

  • University of Wisconsin

    RECRUITING

    Madison, Wisconsin, 53792, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.