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New drug could cut opioid use after knee surgery

NCT ID NCT07548385

First seen Apr 23, 2026 · Last updated Jun 11, 2026 · Updated 9 times

Summary

This study tests whether a new pain medication called Suzetrigine can help people who have knee replacement surgery feel less pain and need fewer opioids. About 235 adults will be randomly assigned to get either Suzetrigine or a placebo before surgery. The goal is to see if the drug reduces both pain scores and the total amount of strong painkillers needed after the operation.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mount Sinai West

    RECRUITING

    New York, New York, 10019, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

The condition(s) this trial relates to.

Pain, Postoperative

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.