No-Stitch eye gel could heal corneal wounds faster
NCT ID NCT07638215
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will test a special gel that can be injected into the eye to seal wounds on the cornea (the clear front part of the eye) without needing stitches. The gel turns from liquid to solid inside the eye and helps the cornea heal naturally. About 30 adults with certain types of corneal damage will take part to see if the gel is safe and works well.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 30 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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May 2026
An estimate. Start dates often move.
- Expected to finish
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Jun 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 85 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * You must meet all the following inclusion criteria to participate in the study: 1. Patients with corneal stromal defects, including those caused by trauma or following lesion excision for infection, with a residual stromal thickness of ≥300 μm in the defect area. 2. Patients aged 18 to 85 years (inclusive, either sex) at the time of consent. 3. Patients who are capable of providing written informed consent voluntarily to participate in the study. Exclusion Criteria: * You will be excluded from the study if you meet any of the following exclusion criteria: 1. Patients with unexplained keratoconjunctival diseases. 2. Patients with severe dry eye, symblepharon, corneal neovascularization, or other ocular surface disorders. 3. Patients with systemic infectious diseases (positive for bacteria/fungi/HBV/HCV/HIV/TP, etc.). 4. Patients with autoimmune diseases such as rheumatoid arthritis, Sjögren's syndrome, or graft-versus-host disease. 5. Patients with uncontrolled ocular diseases in the study eye. 6. Patients with major organ failure or other serious systemic conditions, including but not limited to cardiac insufficiency; poorly controlled diabetes mellitus (fasting blood glucose \>8 mmol/L despite glucose-lowering therapy); uncontrolled stage II or higher hypertension (blood pressure \>160/100 mmHg despite antihypertensive therapy); history of malignancy within the past 5 years; severe immunodeficiency, etc. 7. Patients with psychiatric disorders that may interfere with treatment or evaluation. 8. Pregnant or lactating women, or women planning to become pregnant during the clinical study. 9. Patients deemed unsuitable for participation in the clinical trial by the investigator. 10. Patients unable to complete follow-up visits.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
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