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Can liposuction ease the pain of lipedema? major norwegian trial aims to find out

NCT ID NCT05284266

Symptom relief Sponsor: Haraldsplass Deaconess Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This national study in Norway is testing whether liposuction can reduce pain and improve quality of life for women with lipedema, a chronic condition causing painful fat buildup in the limbs. Researchers will compare early versus delayed liposuction, along with standard treatments like compression therapy. The trial includes 220 women aged 20-65 with significant pain from lipedema.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Liposuction
What this could lead to
If successful, this could provide strong evidence that liposuction effectively reduces pain and improves daily life for women with lipedema, potentially changing treatment guidelines.
What could go wrong
This is an early-stage study without a placebo control, and results may not apply to all patients. Liposuction carries surgical risks like infection or uneven results.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 220 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2022

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

20 to 65 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * female * age 20-65 years * significant pain from lipedema * lipedema stage 1-2 or localized stage 3 Exclusion Criteria: * Non-fluency in the Norwegian language * pregnancy * current malignancy * previous surgical treatment for lipedema * smoking * BMI \> 28 * serious comorbidities such as cardiac-, pulmonary-, renal disease * unwillingness to wear compression garments

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Conditions

The condition(s) this trial relates to.

Lipedema

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Lipedema

Contacts and locations

Locations

  • Haraldsplass Deaconess Hospital

    Bergen, 5009, Norway

More trials for these conditions

Other studies related to the condition(s) this trial covers.