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New hope for rare cancers: drug combo shows promise in shrinking tumors

NCT ID NCT01396408

First seen Apr 20, 2026 · Last updated Jun 17, 2026 · Updated 16 times

Summary

This study tests two drugs, sunitinib and temsirolimus, in 137 people with advanced rare cancers that have no cure. The goal is to see if these drugs can shrink tumors or slow their growth. While not a cure, the approach aims to better control the disease and improve survival.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Allan Blair Cancer Centre

    Regina, Saskatchewan, S4T 7T1, Canada

  • BCCA - Cancer Centre for the Southern Interior

    Kelowna, British Columbia, V1Y 5L3, Canada

  • BCCA - Vancouver Cancer Centre

    Vancouver, British Columbia, V5Z 4E6, Canada

  • CHU Sainte-Justine

    Montreal, Quebec, H3T 1C5, Canada

  • CHUM - Hopital Notre-Dame

    Montreal, Quebec, H2L 4M1, Canada

  • CancerCare Manitoba

    Winnipeg, Manitoba, R3E 0V9, Canada

  • Cross Cancer Institute

    Edmonton, Alberta, T6G 1Z2, Canada

  • Hospital for Sick Children

    Toronto, Ontario, M5G 1X8, Canada

  • Izaak Walton Killam (IWK) Health Centre

    Halifax, Nova Scotia, B3K 6R8, Canada

  • Juravinski Cancer Centre at Hamilton Health Sciences

    Hamilton, Ontario, L8V 5C2, Canada

  • London Regional Cancer Program

    London, Ontario, N6A 4L6, Canada

  • McGill University - Dept. Oncology

    Montreal, Quebec, H2W 1S6, Canada

  • Ottawa Hospital Research Institute

    Ottawa, Ontario, K1H 8L6, Canada

  • QEII Health Sciences Centre

    Halifax, Nova Scotia, B3H 1V7, Canada

  • Saskatoon Cancer Centre

    Saskatoon, Saskatchewan, S7N 4H4, Canada

  • Tom Baker Cancer Centre

    Calgary, Alberta, T2N 4N2, Canada

  • Univ. Health Network-Princess Margaret Hospital

    Toronto, Ontario, M5G 2M9, Canada

Conditions

The condition(s) this trial relates to.

adrenal cortex carcinoma angiosarcoma endometrial clear cell adenocarcinoma Ewing sarcoma familial medullary thyroid carcinoma fibrolamellar hepatocellular carcinoma hemangioblastoma hemangiopericytoma ovarian clear cell cancer paraganglioma pheochromocytoma thymic carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.