New study reveals how sugammadex works in obese patients during surgery
NCT ID NCT05328778
First seen Jun 27, 2026 · Last updated Sep 21, 2026 · Updated 1 time
Summary
This completed Phase 4 trial studied how sugammadex, a drug that reverses muscle relaxants, works in 48 patients undergoing laparoscopic surgery. Researchers measured drug levels in the blood and how quickly patients recovered muscle function. The study focused on patients with a BMI of 25 or higher who were having bariatric surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Sugammadex (a drug that reverses muscle relaxants used during surgery)
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Phase 4
Runs after approval, following long-term safety and how well the treatment works in everyday use.
- Participants
-
48 people
The number who actually took part.
- Started
-
Apr 2022
- Finished
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Apr 2026
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 70 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. ASA: Ⅰ\~Ⅲ 2. BMI≥25kg/m² 3. Patients receiving bariatric surgery. Exclusion Criteria: 1. Pregnant or lactating women 2. Neuromuscular diseases 3. Malignant hyperthermia or allergic history during general anesthesia 4. Drugs that react with rocuronium and vecuronium were taken
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Guangzhou Military Region General Hospital, Department of Anesthesiology
Guangzhou, Guangdong, 510010, China
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