Can a smaller dose of sugammadex rescue patients from prolonged paralysis?
NCT ID NCT05661409
First seen Nov 01, 2025 · Last updated Jun 19, 2026 · Updated 33 times
Summary
This study tested whether low doses of the drug sugammadex can quickly reverse muscle relaxants in surgery patients when the standard reversal drug (neostigmine) doesn't work well enough. 46 adults undergoing elective surgery received one of five different doses of sugammadex or a placebo. The goal was to see how fast muscle function returned, measured by a nerve monitor. The findings could help doctors use less medication while still keeping patients safe.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Grady Memorial Hospital
Atlanta, Georgia, 30303, United States
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Sugammadex
What this could lead to
If successful, this could help anesthesiologists use lower doses of sugammadex as a rescue option, potentially reducing side effects and costs.
What could go wrong
This is a small, early-phase trial with only 46 participants, so results may not apply to all patients. The lowest doses may not work quickly enough.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.