New study maps hidden spread of esophageal cancer
NCT ID NCT07165184
First seen Jun 26, 2026 · Last updated Jun 26, 2026
Summary
This study follows 1,100 people with esophageal cancer to see how often the cancer spreads to a specific lymph node near the windpipe (subcarinal node). Researchers will also look for factors that make spread more likely. The goal is to help doctors decide whether to remove these nodes during surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this study could help surgeons decide when to remove subcarinal lymph nodes during esophageal cancer surgery, potentially improving outcomes.
- What could go wrong
- This is an observational study, not a treatment trial, so it won't directly benefit participants. Results may not apply to all esophageal cancer patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 1,100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2025
- Expected to finish
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Jul 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
patients who had surgery due to esophageal cancer with curative intent
- Ages
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20 to 85 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * patients with esophageal squamous cell carcinoma * clinical staging: cT1-4a N0/+ M0. * no history of other malignancy. Exclusion Criteria: * esophageal cancer in the neck * poor physical status to have esophagectomy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Fudan University Shanghai Cancer Center
RECRUITINGShanghai, Shanghai Municipality, 200032, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Antibody-Drug conjugate targets advanced esophageal cancer after standard treatments fail
- Can a drug combo stop esophageal cancer from returning after surgery?
- Blood proteins may predict who beats esophageal cancer with chemoradiation
- Experimental drug put to the test against Hard-to-Treat GI cancers
- Can a drug combo shrink esophageal tumors before surgery?
- New Antibody-Drug conjugate put to the test against Hard-to-Treat cancers