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New gene-silencing therapy aims to lower stubborn high cholesterol

NCT ID NCT07428473

First seen Feb 23, 2026 · Last updated May 23, 2026 · Updated 9 times

Summary

This early-stage study tests STX-1150, a one-time infusion that temporarily turns off a gene (PCSK9) in the liver to lower bad cholesterol (LDL-C). It does not change your DNA. About 64 adults with high LDL-C will join, and researchers will check safety and how well it works over one year.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Monash Health/ Victorian Heart Hospital (VHH)

    Clayton, Victoria, 3168, Australia

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.