Experimental combo for aggressive lymphoma shows early promise but study halted
NCT ID NCT05896163
First seen Nov 01, 2025 · Last updated May 21, 2026 · Updated 24 times
Summary
This study tested a combination of two experimental drugs (maplirpacept and glofitamab) for people with a type of blood cancer called diffuse large B-cell lymphoma that had come back or not responded to prior treatments. Participants had already tried at least two other treatments and could not have a stem cell transplant. The goal was to find a safe and effective dose. The study was terminated early, so results are limited.
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Barnes-Jewish Hospital Parkview Tower
St Louis, Missouri, 63110, United States
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Gazi University I lcalth Research and Annlica1ion Cenlcr Gazi Hospilal
Ankara, 06560, Turkey (Türkiye)
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National Hospital Organization Kyushu Cancer Center
Fukuoka, 811-1395, Japan
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Rambam Health Care Campus
Haifa, Northern District, 3109601, Israel
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Sheba Medical Center
Ramat Gan, Central District, 5262100, Israel
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Shizuoka Cancer Center
Nagaizumi-cho, Shizuoka, 411-8777, Japan
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Siteman Cancer Center
St Louis, Missouri, 63108, United States
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Sourasky Medical Center
Tel Aviv, TELL ABĪB, 6423906, Israel
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University of Kansas Hospital Cambridge North Tower A
Kansas City, Kansas, 66160, United States
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Washington University School of Medicine
St Louis, Missouri, 63110, United States
Conditions
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