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New hope for kids with tough cancers: drug combo trial launches

NCT ID NCT07444918

First seen Mar 07, 2026 · Last updated Jun 05, 2026 · Updated 15 times

Summary

This study tests a combination of chemotherapy drugs (liposomal irinotecan, vincristine, and temozolomide) with or without an additional drug (anlotinib) in children aged 3-18 whose solid tumors have returned or not responded to treatment. The goal is to see if this combination can shrink tumors and control the disease, while monitoring side effects. About 33 participants will receive treatment in 21-day cycles, with regular check-ups to track progress.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Ewing sarcoma osteosarcoma Recurrence rhabdomyosarcoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.