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Large study aims to predict stroke in silent artery disease

NCT ID NCT07156344

Knowledge-focused Sponsor: Xuanwu Hospital, Beijing Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This completed observational study followed 3,849 people with asymptomatic intracranial atherosclerosis (narrowing of brain arteries) to better understand how the disease progresses and to improve stroke prediction. Participants underwent routine imaging and cognitive tests over time. The goal is to identify which plaques are dangerous and to develop better screening and prevention strategies.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could lead to better ways to predict and prevent stroke in people with asymptomatic intracranial atherosclerosis.
What could go wrong
This is an observational study, not a treatment trial, so it cannot directly improve health. Results may not apply to all populations or lead to immediate clinical changes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

3,849 people

The number who actually took part.

Started

Jan 2019

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Transcranial Doppler (TCD)-detected asymptomatic intracranial atherosclerotic patients

Ages

30 to 80 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Intracranial arterial stenosis confirmed by transcranial Doppler (TCD), clinically suspected to be of atherosclerotic origin * No history of stroke or transient ischemic attack (TIA) * Adequate temporal bone acoustic window penetrability Exclusion Criteria: * Clinically diagnosed non-atherosclerotic etiology-related intracranial arterial stenosis * Poor temporal bone acoustic window penetrability * Loss to follow-up

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Conditions

The condition(s) this trial relates to.

cerebral artery stenosis intracranial arteriosclerosis stroke disorder prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Asymptomatic intracranial atherosclerotic stenosis patients

Contacts and locations

Locations

  • Xuanwu Hospital, Capital Medical University

    Beijing, Beijing Municipality, 100053, China