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Shock to the system: can zaps help stroke survivors walk again?

NCT ID NCT07211672

Symptom relief Sponsor: TOPMED Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a device that sends mild electrical pulses to leg muscles can help people who had a stroke 6-12 months ago walk better. Five participants will complete 24 gait training sessions over 8-12 weeks. Researchers will measure changes in walking speed, endurance, and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Multichannel functional electrical stimulation device (Neuroskin)
What this could lead to
If it works, this could point toward a new therapy to help stroke survivors walk faster and with more confidence.
What could go wrong
This is a very small, early study with only 5 people. It may not show clear benefits, and results may not apply to all stroke survivors.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 5 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2025

An estimate. Start dates often move.

Expected to finish

Feb 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * First ischemic stroke or first hemorrhagic supratentorial stroke * Stroke must be unique * Stoke event in the last 12 months but no sooner than 6 months (post subchronic stroke phase) * Able to walk with the support of one person and one or multiple walking aids (new functionnal ambulatory classification equal to 1, 2 or 3) * Able to tolerate and respond to electrical stimulation(Muscle strength grading level 3 while having the quadriceps stimulated) * Willing to delay anti-spastic treatments like botulinic toxins and motor blockers until the end of the rehabilitation period included in the protocol Exclusion Criteria: * Multiple strokes * Does not respond sufficiently to electrical stimulation * Contraindication to electrical stimulation * Comprehension, psychiatric or cognitive problems that could hamper the protocol * Bilateral stroke or subtentorial stroke * Able to walk without the support of one person (new functionnal ambulatory clssification equal to 4 or more) * Needing help from more than one person to walk (new functionnal ambulatory classification equal to 0) * Moderate spasticity in one or more lower body muscle groups (Modified Ashworth Scale Score \>= 2)

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Stroke ( 3 months after onset) Stroke sequelae

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.