Which therapy helps stroke survivors move better? new trial tests mirror vs. constraint therapy
NCT ID NCT07668349
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two rehabilitation techniques—mirror therapy and modified constraint-induced movement therapy—to see which better improves arm function in people who had a stroke. Sixteen participants with hemiplegia (weakness on one side) will be randomly assigned to one of the therapies for four weeks. The goal is to find which approach leads to greater gains in movement, daily activity, and independence.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- mirror therapy and modified constraint-induced movement therapy (mCIMT)
- What this could lead to
- If this trial succeeds, it could show which therapy better helps stroke survivors regain arm movement and daily independence.
- What could go wrong
- This is a small, early-stage trial with only 16 participants, so results may not apply to all stroke patients. Both therapies are low-risk but may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 16 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Feb 2026
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * \* Diagnosis: Confirmed first ischemic or hemorrhagic stroke with clinical and neurological evaluation. * Time Since Stroke: 3 to 24 months post-stroke onset. * Hemiplegia: Significant motor deficit in the affected upper extremity. * Motor Function Level: Presence of mild to moderate motor impairment in the affected upper extremity (FMA-UE score appropriate for the application of modified CIMT and mirror therapy). * Cognitive Status: Adequate cognitive capacity to understand and follow the study protocols (Mini-Mental State Examination score of 20 or above). * Visual Perception: Adequate visual perception to perform mirror therapy. * Comorbidities: Absence of severe coexisting medical conditions that prevent participation (e.g., uncontrolled cardiovascular diseases, severe psychiatric disorders). * Prior Treatments: No prior intensive participation in the interventions investigated in this study (modified CIMT or mirror therapy). * Consent: Voluntary agreement to participate and signed informed consent form. Exclusion Criteria: * \* Uncontrolled diabetes or other metabolic disorders. * Progressive non-stroke neurological diseases (e.g., Parkinson's disease, multiple sclerosis). * Terminal illness or short life expectancy. * Severe cognitive impairment preventing comprehension or execution of the study protocols (e.g., advanced dementia). * Severe visual impairment that prevents mirror therapy application (e.g., uncorrected visual acuity loss, neglect). * Severe visuospatial perception disorders making it difficult to perceive or interpret the mirror image. * Absence or minimal level of active movement in the affected upper extremity (limiting the applicability of modified CIMT). * Significant motor deficit in the unaffected upper extremity. * Severe and uncontrolled spasticity in the upper extremity.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Akay Special Education and Rehabilitation Center
RECRUITINGKastamonu, Merkez, 37100, Turkey (Türkiye)