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Stress hormones linked to implant gum disease, study finds

NCT ID NCT07353515

Knowledge-focused Sponsor: Inonu University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether stress plays a role in gum disease around dental implants. Researchers measured stress hormones and anxiety levels in 62 adults with healthy implants, mild gum inflammation, or more serious implant-related gum disease. The goal was to understand how stress might affect implant health, but the study did not test any treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

62 people

The number who actually took part.

Started

Feb 2023

Finished

Jun 2024

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consisted of adult individuals aged 18-65 years with at least one functional dental implant. Participants were selected from patients attending the Department of Periodontology, Faculty of Dentistry, Inonu University, and were classified into peri-implant health, peri-implant mucositis, or peri-implantitis groups based on clinical and radiographic criteria.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Being volunteer to participate in the study * Adults aged 18 to 65 years. * Systemically healthy individuals. * No periodontal treatment within the past 6 months. * No self-reported psychiatric disorders. * No use of antibiotics within the past 6 months. * No use of steroid, immunosuppressive, or psychiatric medications. * No clinically evident oral infection. * Not pregnant and not breastfeeding. * Not smoking * Maintaining oral hygiene Exclusion Criteria: * Age younger than 18 years or older than 65 years. * History of periodontal treatment within the past 6 months. * Use of antibiotics within the past 6 months. * Inadequate or contaminated peri-implant sulcular fluid samples. * Pregnancy or breastfeeding. * Long-term corticosteroid usage.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Depression Peri-Implantitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Peri implant mucositis Peri-implant health Peri-implantitis

Contacts and locations

Locations

  • Inonu University, Faculty of Dentistry

    Malatya, Battalgazi, 44280, Turkey (Türkiye)

More trials for these conditions

Other studies related to the condition(s) this trial covers.