Simple blood test may predict Post-Surgery delirium risk
NCT ID NCT07194096
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a simple blood sugar measurement, called the stress hyperglycemia ratio (SHR), can help predict which patients will develop delirium (sudden confusion) after surgery. Researchers will analyze medical records from 15,000 adults who had non-brain, non-heart surgery. The goal is to find a reliable way to identify high-risk patients early so that preventive steps can be taken.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could lead to a simple blood test to identify patients at high risk for delirium after surgery, allowing for early preventive care.
- What could go wrong
- This is a retrospective study, meaning it looks back at existing data. It can show a link but cannot prove cause and effect. The results may not apply to all surgery types.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 15,000 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Oct 2025
An estimate. Start dates often move.
- Expected to finish
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Nov 2025
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Adult patients aged 18 years or older who underwent non-neurosurgical and non-cardiac surgical procedures at Tongji Hospital between 2014 and 2024 were included.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged ≥18 years * Underwent non-neurosurgical and non-cardiac surgical procedures * For patients with multiple qualifying surgical procedures during the study period, only data from the first eligible surgery were analyzed Exclusion Criteria: * American Society of Anesthesiologists (ASA) physical status V * Procedural sedation or anesthesia performed outside the operating room, or total anesthesia duration ≤60 minutes * Preoperative delirium or dementia * Insufficient laboratory data for calculating the stress hyperglycemia ratio (SHR) * Missing values for essential confounding variables required for multivariable analysis
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Could a sleep drug shield older hearts from post-surgery delirium?
- Could a common sedative shield aging brains from Post-Surgery delirium?