Can a simple screening program stop opioid addiction before it starts?
NCT ID NCT06527599
First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time
Summary
This study tests a program designed to prevent opioid misuse in people hospitalized for a traumatic injury. Participants complete brief questionnaires about pain and opioid use risk, and receive enhanced care coordination based on their responses. The goal is to see if this adaptive approach is practical and acceptable for patients and staff, paving the way for a larger trial.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Opioid Risk Monitoring and enhanced Trauma Care Coordination
- What this could lead to
- If successful, this approach could provide a practical, scalable way to identify and support trauma patients at risk for opioid misuse, potentially preventing addiction.
- What could go wrong
- This is a small pilot study focused on feasibility, not effectiveness. The program may not reduce opioid misuse in a larger, more diverse population.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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118 people
The number who actually took part.
- Started
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Aug 2024
- Expected to finish
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Dec 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Able to speak, read, and write fluently in English. * Admission to site hospital for a traumatic injury at time of screening. A traumatic injury is defined as a physical injury with sudden onset requiring immediate medical attention. * Injury severity score of 9 or greater. * Meets at least one of the following descriptions below: * Received 40 mg morphine milligram equivalent (MME) within 48 hours of pre-screening; or * Discharged with a prescription for an opioid medication. * Expected to be in control of their own medications at the time of discharge from the controlled environment of hospital or short-term rehabilitation. Exclusion Criteria: * Inability to provide written consent for any reason. * Current self-reported diagnosis of cancer with life expectancy less than 12 months at time of screening. * Current prescription for opioid use disorder (e.g., suboxone, buprenorphine, methadone, naltrexone), with a current diagnosis of opioid use disorder (OUD) (mild or greater) not in remission. * History of dementing illnesses and other neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, or vascular dementia. * Current significant traumatic brain injury (defined as the presence of any intracranial blood on Computed Tomography scan of the head or best Glasgow Coma Scale Score of less than 13 at the time of screening). * Current spinal cord injury with persistent neurologic deficit at the time of screening. * Acute stroke immediately prior to/upon admission, or emergent stroke as a new event during hospitalization. * Any vision or hearing impairments resulting in an inability to complete study procedures. * Current pregnancy, as indicated by chart review and self-report. * Involved in any criminal justice proceedings related to illicit substance use at time of screening. * Incarcerated or in police custody at time of study enrollment. * Admitted to the hospital with a burn affecting \>10% total body surface area, as indicated by chart review. * Any medical, physical, cognitive, or psychiatric conditions that would limit the participant's ability to provide informed consent or complete study procedures, as determined by study staff and/or investigators.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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UW Health
Madison, Wisconsin, 53792, United States
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Other studies related to the condition(s) this trial covers.
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