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Immune booster trial offers new hope for kids with Tough-to-Treat cancer

NCT ID NCT06450041

First seen Nov 05, 2025 · Last updated May 20, 2026 · Updated 27 times

Summary

This study tests a new treatment for children and young adults with neuroblastoma that has come back or not responded to standard therapy. It combines chemotherapy drugs (temozolomide, irinotecan) with an antibody (dinutuximab) and special immune cells called NK cells from a healthy donor. The goal is to see if this combination can shrink tumors or stop the cancer from growing.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Boston Children's Hospital, Dana-Farber Cancer Institute.

    NOT_YET_RECRUITING

    Boston, Massachusetts, 02115, United States

    Contact

  • C.S Mott Children's Hospital

    NOT_YET_RECRUITING

    Ann Arbor, Michigan, 48109, United States

    Contact

  • Children's Hospital Colorado

    NOT_YET_RECRUITING

    Aurora, Colorado, 80045, United States

    Contact

  • Children's Hospital Los Angeles

    RECRUITING

    Los Angeles, California, 90027-0700, United States

    Contact

  • Children's Hospital of Philadelphia

    RECRUITING

    Philadelphia, Pennsylvania, 19104-4318, United States

    Contact

  • Cincinnati Children's Hospital Medical Center

    NOT_YET_RECRUITING

    Cincinnati, Ohio, 45229-3039, United States

    Contact

  • Comer Children's Hospital, University of Chicago

    NOT_YET_RECRUITING

    Chicago, Illinois, 60614, United States

    Contact Email: •••••@•••••

  • Cook Children's Medical Center

    RECRUITING

    Fort Worth, Texas, 76104, United States

    Contact

  • Nationwide Children's Hospital

    NOT_YET_RECRUITING

    Columbus, Ohio, 43205, United States

    Contact

  • Seattle Children's Hospital

    NOT_YET_RECRUITING

    Seattle, Washington, 98105, United States

    Contact

  • St. Jude Children's Research Hospital

    NOT_YET_RECRUITING

    Memphis, Tennessee, 38105, United States

    Contact

  • UCSF Benioff Children's Hospital

    NOT_YET_RECRUITING

    San Francisco, California, 94143, United States

    Contact

  • University of Texas Southwestern

    RECRUITING

    Dallas, Texas, 75235, United States

    Contact

Conditions

Explore the condition pages connected to this study.