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Can one steroid shot ease deep neck infections?

NCT ID NCT07815028

Symptom relief Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 11, 2026 · Last updated Sep 11, 2026

Summary

Deep neck infections cause severe pain and swelling that can make it hard to open the mouth or swallow. Researchers are testing whether a single intravenous dose of dexamethasone, given alongside standard treatment, reduces pain and swelling better than a placebo. The trial enrolls adults with a confirmed deep neck infection and follows their pain scores, mouth opening, and temperature for up to seven days.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
dexamethasone, a steroid given as a single intravenous dose
What this could lead to
If it helps, a single steroid dose could become a simple add-on that eases pain and swelling for people with deep neck infections.
What could go wrong
This is a small trial of 32 people, so any hint of benefit may not hold up in larger studies. Steroids can raise blood sugar and may not suit everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

32 people

The number who actually took part.

Started

Mar 2025

Finished

Jun 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * age 18 years or older * diagnosis of a deep neck space infection confirmed by clinical examination and contrast-enhanced computed tomography * provision of written informed consent Exclusion Criteria: * Isolated peritonsillar abscess * Age younger than 18 years * Systemic corticosteroid use before enrollment * Hospitalization for a diagnosed or suspected deep neck infection within the preceding 30 days

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Deep neck infections

Contacts and locations

Locations

  • Kartal Dr. Lutfi Kirdar City Hospital

    Istanbul, Istanbul, 34865, Turkey (Türkiye)