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Brain scans may reveal why some kids with cerebral palsy improve with physical therapy

NCT ID NCT07752030

Knowledge-focused Sponsor: Father Flanagan's Boys' Home Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 07, 2026 · Last updated Aug 07, 2026

Summary

This study explores why some people with cerebral palsy respond well to gait training while others do not. Researchers will track brain activity and walking ability weekly during an 8-week physical therapy program in 20 participants. The goal is to identify brain patterns that predict who benefits most, potentially leading to more personalized therapy approaches.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Physical therapy gait training
What this could lead to
If successful, this could lead to personalized physical therapy for cerebral palsy, where treatments are tailored to an individual's brain activity to maximize mobility gains.
What could go wrong
This is a small, early-stage study with only 20 participants, so results may not apply to everyone with cerebral palsy. The focus is on understanding brain changes, not on proving a treatment works, and the therapy itself may not improve mobility for all.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Aug 2026

An estimate. Start dates often move.

Expected to finish

Jun 2030

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 30 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Persons with a diagnosis of cerebral palsy. Exclusion Criteria: * Participants not able to stand or initiate gait movement without assistance. * Unable to walk for 1-minute with or without a mobility aide (i.e., forearm crutches, wheeled walker) * Have had orthopedic surgery within the last 6 months. * Metal in their body that would preclude neuroimaging. * Current pregnancy or suspected pregnancy. * Currently on steroid medication (i.e., birth control).

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Conditions

The condition(s) this trial relates to.

cerebral palsy Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebral palsy (CP)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Boys Town National Research Hospital

    Omaha, Nebraska, 68010, United States

More trials for these conditions

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