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New stem cell hope for kids with 'Bubble Boy' diseases

NCT ID NCT02990819

First seen Nov 11, 2025 · Last updated May 25, 2026 · Updated 22 times

Summary

This study tests a stem cell transplant from a donor to treat children and young adults with life-threatening immune system problems. The goal is to replace the faulty immune system with a healthy one from the donor. Participants receive chemotherapy before the transplant to prepare their body, and the donor cells are specially treated to reduce side effects. The study aims to see if this approach leads to stable, long-term immune function.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

Conditions

Explore the condition pages connected to this study.