Can your own stem cells ward off COVID-19?
NCT ID NCT04349631
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether five infusions of a person's own stem cells (HB-adMSCs) could prevent COVID-19 symptoms and hospitalization in 51 high-risk adults, such as those over 65 or with underlying health conditions. Participants had previously banked their cells at Hope Biosciences. The goal was to see if the treatment could boost the immune system and reduce severe illness.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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51 people
The number who actually took part.
- Started
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Apr 2020
- Finished
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Nov 2020
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: Subjects must meet the criteria for 1,2, OR 3, AND 4-7 to be eligible. 1. Men, and women 65 years of age or older (according to CDC provisions) OR 2. Participant works in healthcare facility or other well characterized high-risk environment OR 3. Has underlying conditions including but not limited to cardiopathies, diabetes mellitus, cancer, COPD, asthma or any other systemic autoimmune disease. 4. Subject must have previously banked their cells at Hope Biosciences 5. No signs or symptoms of infection, including but not limited to, body temperature \>100 F and pulse rate \> 100 BPM. 6. Subject provides written informed consent prior to initiation of any study procedures. 7. Agrees to the collection of venous blood per protocol. 8. Agrees to conformational testing for SARS-CoV-2 before end of study. Exclusion Criteria: Subjects must not have any of the following criteria to be eligible. 1. Women who are pregnant or lactating, or those who are not pregnant but do not take effective contraceptive measures 2. Patients who are participating in other clinical trials or have intake of investigational drug within the previous 30 days; 3. Inability to provide informed consent or to comply with test requirements; 4. Any medical disease or condition that, in the opinion of the site PI or sub-investigator, precludes study participation. Including acute, subacute, intermittent or chronic medical disease or condition that would place the subject at an unacceptable risk of injury, render the subject unable to meet the requirements of the protocol, or may interfere with the evaluation of responses or the subject's successful completion of this trial. 5. Patients who have received a stem cell treatment within one year. 6. Receipt of any other SARS-CoV-2 or other experimental coronavirus vaccine at any time prior to or during the study. 7. Patient currently or recently symptomatic for COVID-19 or anyone with COVID-19 associated symptoms within the past 30-days
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Hope Biosciences Stem Cell Research Foundation
Sugar Land, Texas, 77478, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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