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Experimental cancer drug trial halted early

NCT ID NCT06188208

First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 36 times

Summary

This early-stage study tested a new drug called VVD-130850, which blocks a protein (STAT3) that helps cancers grow. The trial aimed to find a safe dose and see if the drug works, both alone and with another immunotherapy, in people with advanced solid tumors or blood cancers. The study was terminated before completion, so results are limited.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Blacktown Hospital

    Blacktown, New South Wales, Australia

  • California Research Institute

    Los Angeles, California, 90027, United States

  • Cancer Research South Australia

    Adelaide, Australia

  • Florida Cancer Specialists

    Sarasota, Florida, 34232, United States

  • Gold Coast University Hospital

    Southport, Queensland, Australia

  • Hospital Universitario 12 de Octubre

    Madrid, Spain

  • ICON Cancer Research

    South Brisbane, Australia

  • MDACC

    Houston, Texas, 77030, United States

  • NEXT Austin

    Austin, Texas, 78758, United States

  • NEXT Dallas

    Irving, Texas, 75039, United States

  • NEXT Madrid

    Madrid, Spain

  • NEXT San Antonio

    San Antonio, Texas, 78299, United States

  • NEXT Virginia

    Fairfax, Virginia, 22031, United States

  • Orange Health Service

    Orange, New South Wales, Australia

  • START Barcelona Hospital HM Nou Delfos

    Barcelona, Spain

  • START Madrid CIOCC

    Madrid, Spain

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

  • Start Madrid-FJD, Hospital Fundacion Jimenez Diaz

    Madrid, Spain

  • University of Utah Huntsman Cancer Institute

    Salt Lake City, Utah, 84112, United States

  • Vall d'Hebron

    Barcelona, Spain

Conditions

The condition(s) this trial relates to.

hematopoietic and lymphoid system neoplasm neoplasm non-Hodgkin lymphoma non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.