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Gene therapy SPOT-03 aims to rebuild muscle protein in boys with duchenne

NCT ID NCT07188012

First seen Sep 30, 2025 · Last updated May 20, 2026 · Updated 24 times

Summary

This early-phase study tests a gene therapy called SPOT-03 in 9 boys with Duchenne muscular dystrophy (DMD). The main goal is to see if the treatment is safe and tolerable. Researchers will also check if the therapy increases dystrophin protein levels in muscles, which is missing in DMD. The study is currently recruiting boys aged 2 to under 8 years who can walk at least 10 meters.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Shanghai Children's Medical Center

    RECRUITING

    Shanghai, Shanghai Municipality, China

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.