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Gene therapy trial hopes to slow Huntington's with single brain injection

NCT ID NCT06826612

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 24 times

Summary

This study tests a new gene therapy called SPK-10001 for people with Huntington's disease. The treatment is given once directly into the brain. The goal is to see if it is safe and can slow down the disease. About 53 adults with early-stage Huntington's will take part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Ohio State University

    RECRUITING

    Columbus, Ohio, 43221, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • University of Cincinnati/Cincinnati Children's Hospital

    RECRUITING

    Cincinnati, Ohio, 45221, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Pennsylvania

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

  • University of Pittsburg

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

Conditions

Explore the condition pages connected to this study.