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Massive new study to track spine tumor patients after surgery and radiation

NCT ID NCT07225491

Knowledge-focused Sponsor: Ohio State University Comprehensive Cancer Center Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Aug 19, 2026 · Updated 3 times

Summary

This study is following 3,000 adults with spine tumors (either primary or that have spread from elsewhere) who undergo surgery to relieve pressure on the spine, followed by radiation. Researchers are tracking how long patients live, whether the tumor stays under control, and how well the hardware used in surgery holds up. The goal is to gather real-world data to improve future treatment plans.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this study could provide clearer data on how well surgery plus radiation works for spine tumors, helping doctors make better treatment decisions.
What could go wrong
This is an observational study, not a test of a new treatment. It cannot prove what works best, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 3,000 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Dec 2037

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population will be comprised of patients with primary and metastatic spine disease who undergo surgery followed by radiation therapy. Patients may be enrolled regardless of previous local or systemic treatments received prior to enrollment in this registry. Patients may be enrolled regardless of other current local or systemic treatments of disease extent.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of primary or metastatic disease to the spine who undergo surgical decompression and stabilization followed by radiation therapy Exclusion Criteria: * Inability to obtain a standard MRI or CT / CT myelogram for radiation treatment planning and dosimetry * Inability to receive radiation treatment. * Patients under 18 years of age

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Conditions

The condition(s) this trial relates to.

metastatic carcinoma in the bone spinal cord cancer spinal cord neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Spine cancer Spine metastases Spine tumor

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The study's own enquiry address

    This study publishes an address for enquiries. See it below .

  2. The places running it

    5 sites. The list below names each one and where it is.

  3. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  4. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Study contacts

  • Contact

    Email: •••••@•••••

Locations

  • Indiana University

    NOT_YET_RECRUITING

    Indianapolis, Indiana, 46202, United States

  • Rutgers Robert wood Johnson Medical School

    RECRUITING

    New Brunswick, New Jersey, 08901, United States

  • The Ohio State University Wexner Medical Center

    RECRUITING

    Columbus, Ohio, 43210, United States

  • University of Maryland,

    NOT_YET_RECRUITING

    Baltimore, Maryland, 21201, United States

  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

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