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Does anesthesia choice affect inflammation after knee surgery?

NCT ID NCT07214558

Knowledge-focused Sponsor: Elazıg Fethi Sekin Sehir Hastanesi Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at how spinal versus general anesthesia affects inflammation after total knee replacement. Researchers measured a blood marker called Delta Neutrophil Index in 84 patients. The goal was to see if one type of anesthesia leads to less inflammation, but no new treatment was tested.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

84 people

The number who actually took part.

Started

Sep 2025

Finished

Oct 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adult patients undergoing elective total knee arthroplasty at Elazig Fethi Sekin City Hospital, Department of Anesthesiology and Reanimation.

Ages

18 to 99 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients scheduled for total knee arthroplasty * Age ≥ 18 years * ASA physical status classification I-III Exclusion Criteria: * Active infection * Hematologic disease (e.g., leukemia, aplastic anemia) * Autoimmune or chronic inflammatory disease * Use of corticosteroids or immunosuppressive drugs * Malignancy * Acute trauma or sepsis * Pregnancy

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Inflammatory response in total knee arthroplasty

Contacts and locations

Locations

  • University of Health Sciences, Elazığ Fethi Sekin City Hospital

    Elâzığ, Merkez, 23200, Turkey (Türkiye)