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Spinal cracking for neck pain: does it really work?

NCT ID NCT03576846

First seen Jan 05, 2026 · Last updated Jun 22, 2026 · Updated 25 times

Summary

This study tested whether spinal manipulation therapy, combined with stretching, can reduce neck pain and affect heart rate variability in 131 adults with long-term neck pain. Participants were randomly assigned to receive either spinal manipulation plus stretching or stretching alone. The study also explored whether a pain modulation test could predict who benefits most.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Danvik Kiropraktik och Rehab

    Stockholm, Sweden

  • Karolinska Institutet

    Stockholm, 171 77, Sweden

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

spinal manipulation and stretching exercises

What this could lead to

If successful, this could show that spinal manipulation helps ease neck pain and improve nervous system function.

What could go wrong

This is a small, completed study. Results may not apply to everyone with neck pain, and the effects might be modest.

Conditions

The condition(s) this trial relates to.

Neck Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.