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Spine zaps may boost arm recovery after spinal injury

NCT ID NCT07208188

Symptom relief Sponsor: NHS Greater Glasgow and Clyde Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This early study tests whether delivering small electrical pulses over the skin above the spinal cord, alongside standard therapy, can help people with a recent spinal cord injury regain arm and hand function. Twenty participants will receive either active or sham stimulation during their regular therapy sessions for four weeks. The main goal is to see if this approach is practical and acceptable, not yet to prove it works.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcutaneous spinal cord stimulation (tESCS)
What this could lead to
If it works, this could point toward a way to help people with new spinal cord injuries regain arm and hand function faster and more fully.
What could go wrong
This is a very early feasibility study with only 20 participants, so it is designed to test practicality, not effectiveness. The results may not lead to a proven treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

About 20 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Nov 2025

An estimate. Start dates often move.

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Aged 18 years or over, both sexes. * At least 6 weeks post-implant (in participants having a surgery for an implant to stabilise the spine). * ISNCSCI upper extremity motor score between 5 and 30 (both arms/hands) * GRASSP-strength score \>=15 \& \<70 * Medically stable, cognitively intact and able to breathe independently. * Attending upper limb therapy sessions at the QENSIU * Planned stay longer than the duration of the intervention * Able to sit for more than 2 hours a day Exclusion Criteria: * Unstable cervical spine injury * Needing ventilation assistance during daytime * Any implanted active metallic device without unconfirmed MRI compatibility (in our previous studies, we safely applied tESCS to participants with MRI-compatible devices/implants) * Pregnancy and/or lactation. * Non-injury-related neurological impairment * Severe spasticity which have been unstable prior to enrolment * Botulinum toxin injections- * Clinically significant severe depression * Patients who have cardiovascular disease * Patients with severe ongoing Autonomic Dysreflexia * Skin conditions or allergies that may affect electrode placement. * Current infections * Patients who have been involved in any other interventional study

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Conditions

The condition(s) this trial relates to.

quadriplegia spinal cord injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Spinal cord injuries (SCI)

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Queen Elizabeth National Spinal Injuries Unit

    Glasgow, G51 4TF, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.