Spinal implant + robot rehab: a new hope for walking after injury?
NCT ID NCT02936453
First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time
Summary
This trial tests whether a spinal implant that delivers electrical stimulation, combined with robot-assisted rehabilitation, can improve walking ability in people with chronic spinal cord injury. Participants will have a device implanted and then undergo months of training. The goal is to see if this approach is safe and can help them walk better and faster.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- spinal epidural electrical stimulation (EES) combined with robot-assisted rehabilitation
- What this could lead to
- If successful, this approach could help people with spinal cord injury walk better and faster, potentially improving independence and quality of life.
- What could go wrong
- This is an early, first-in-human study with a small number of participants, so success is not guaranteed. There are risks from surgery and device implantation, and the benefits may not be seen in all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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12 people
The number who actually took part.
- Started
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Jul 2016
- Finished
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Jul 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age 18-65 (women or men) * Incomplete SCI graded as AIS A,B,C \& D * Level of lesion: T10 and above, based on AIS level determination by the PI, with preservation of conus function * The intact distance between the cone and the lesion must be at least 60mm * Focal spinal cord disorder caused by either trauma or epidural, subdural or intramedullary bleeding * Minimum 12 months post-injury * Completed in-patient rehabilitation program * Able to stand with walker or 2 crutches * Stable medical and physical condition as considered by Investigators * Adequate care-giver support and access to appropriate medical care in patient's home community * Agree to comply in good faith with all conditions of the study and to attend all required study training and visits * Must participate in two training sessions before enrolment * Must provide and sign Informed Consent prior to any study related procedures Exclusion Criteria: * Limitation of walking function based on accompanying (CNS) disorders (systemic malignant disorders, cardiovascular disorders restricting physical training, peripheral nerve disorders) * History of significant autonomic dysreflexia * Cognitive/brain damage * Epilepsy * Patient who has spinal canal stenosis * Patient who uses an intrathecal Baclofen pump. * Patient who has any active implanted cardiac device such as pacemaker or defibrillator. * Patient who has any indication that would require diathermy. * Patient who has any indication that would require MRI. * Patient that have an increased risk for defibrillation * Severe joint contractures disabling or restricting lower limb movements. * Haematological disorders with increased risk for surgical interventions (increased risk of haemorrhagic events). * Participation in another locomotor training study. * Congenital or acquired lower limb abnormalities (affection of joints and bone). * Women who are pregnant (pregnancy test obligatory for woman of childbearing potential) or breast feeding or not willing to take contraception. * Known or suspected non-compliance, drug or alcohol abuse. * Spinal cord lesion due to either a neurodegenerative disease or a tumour. * Patient has other anatomic or co-morbid conditions that, in the investigator's opinion, could limit the patient's ability to participate in the study or to comply with follow-up requirements, or impact the scientific soundness of the study results. * Patient is unlikely to survive the protocol follow-up period of 12 months.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre Hospitalier Universitaire Vaudois
Lausanne, Canton of Vaud, 1011, Switzerland
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Other studies related to the condition(s) this trial covers.
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