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Which spinal anesthetic works best for C-Sections?

NCT ID NCT06680167

Symptom relief Sponsor: Sohag University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compared two spinal anesthetics—prilocaine and bupivacaine—in 142 women having planned C-sections. Researchers measured how quickly each drug caused numbness and muscle relaxation, and how long those effects lasted. The goal was to see if prilocaine could be a good alternative to the standard bupivacaine.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
hyperbaric prilocaine 2% and hyperbaric bupivacaine 0.5%
What this could lead to
If prilocaine works as well as bupivacaine, it could offer a faster-recovering option for spinal anesthesia during C-sections.
What could go wrong
This is a small, early-phase study (142 women) comparing two drugs already in use. Results may not apply to all patients or settings.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Early phase 1

The earliest testing in people: a first look at safety, in a very small group.

Participants

142 people

The number who actually took part.

Started

Oct 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Women aged 18-45 years. 2. Patients with uncomplicated pregnancies. 3. American society of anesthesiologist (ASA) physical status I or II. 4. Height between 155 cm and 175 cm. 5. Written informed consent provided. - Exclusion Criteria: 1. Patients with known allergies to local anesthetics. 2. Contraindications to intrathecal anesthesia (e.g., infection at the injection site and coagulopathy). 3. Severe preeclampsia or eclampsia. 4. Presence of significant comorbidities (e.g., uncontrolled diabetes, hypertension, renal or hepatic dysfunction). 5. History of spinal surgery or significant spinal deformity. 6. Patients who refuse to participate in the study -

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Spinal anesthesia

Contacts and locations

Locations

  • Sohag University Hospitals

    Sohag, Sohag Governorate, 82749, Egypt

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