New brain scans could sharpen diagnosis of lewy body dementia
NCT ID NCT00917709
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study used special brain scans (SPECT imaging) to look at two key brain chemicals—acetylcholine and dopamine—in people with dementia with Lewy bodies. Researchers aimed to see if differences in these chemicals could help diagnose the disease and identify subtypes. The study included 34 participants and was completed, but it was an observational imaging study, not a treatment trial.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If successful, this could help doctors better diagnose dementia with Lewy bodies and identify different types of the disease.
- What could go wrong
- This was a small, early-stage imaging study with only 34 participants, so results may not apply to everyone. It did not test a treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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34 people
The number who actually took part.
- Start date
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May 2009
- Finished
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Oct 2013
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 90 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients: man or woman probable DLB, with and without extrapyramida syndrome * Healthy subjects: man or woman with no neuropsychiatric disorders Exclusion Criteria: * Diagnostic or therapeutic irradiation during the 12 months before SPECT imaging * Age less than 18 and more than 90 * Iodine sensibility * Brain-vascular disease, severe brain injury, type I and II diabetes mellitus, thyroid dysfunction, chronic alcoholism * Pregnant and breast feeding women, women in age to procreate * Impossibility to undergo MRI study (pace-maker, claustrophobia) * Persons under guardianship, outside state to express their assent or in emergency situation * Healthy subjects: cognitive impairment, dementia
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Groupe Hospitalier Pellegrin - C.H.U. de Bordeaux
Bordeaux, 33076, France
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