New hope for kids with tough cancer: drug combo trial launches
NCT ID NCT02298348
First seen Mar 26, 2026 · Last updated Apr 29, 2026 · Updated 3 times
Summary
This early-phase study tests a three-drug combination (sorafenib, cyclophosphamide, and topotecan) in children and young adults with neuroblastoma that has come back or not responded to treatment. The main goal is to find the safest dose of sorafenib when given with the other two drugs. Up to 18 participants under age 30 will be enrolled to monitor side effects and determine the best dose for future studies.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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C.S Mott Children's Hospital
Ann Arbor, Michigan, 48109, United States
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Children Hospital of Colorado
Aurora, Colorado, 80045, United States
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Children's Healthcare of Atlanta
Atlanta, Georgia, 30322, United States
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Children's Hospital Los Angeles
Los Angeles, California, 90027-0700, United States
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Children's Hospital and Regional Medical Center - Seattle
Seattle, Washington, 98105, United States
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Childrens Hospital Boston, Dana-Farber Cancer Institute.
Boston, Massachusetts, 02115, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229-3039, United States
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Cook Children's Healthcare System
Fort Worth, Texas, 76104, United States
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Hospital for Sick Children
Toronto, Ontario, M5G 1X8, Canada
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UCSF Comprehensive Cancer Center
San Francisco, California, 94143, United States
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University of Chicago, Comer Children's Hospital
Chicago, Illinois, 60637, United States
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University of North Carolina
Chapel Hill, North Carolina, 27599, United States
Conditions
Explore the condition pages connected to this study.