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Could tight clothing and dance help EDS patients regain balance?

NCT ID NCT04020107

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether wearing compression garments and doing specific physiotherapy exercises could improve balance and quality of life in people with hypermobile Ehlers-Danlos syndrome (hEDS). Forty patients with hEDS were followed for a year, first receiving standard care, then adding compression garments and proprioceptive physiotherapy, and finally doing adapted physical activity including dance and stretching. The main goal was to see if these treatments improved postural control measured on a force platform.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
compression garments and proprioceptive physiotherapy
What this could lead to
If it works, this could offer a non-drug approach to improve balance and daily function for people with hypermobile Ehlers-Danlos syndrome.
What could go wrong
This was a small, early-stage study with only 40 patients and no control group for the main intervention. Results may not apply to all patients or be long-lasting.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

40 people

The number who actually took part.

Started

May 2018

Finished

Nov 2022

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: For EDS patients : * Subjects aged 18 to 40, * SEDh patients newly diagnosed for less than 2 years according to international criteria of 2017, * Having a Body Mass Index (BMI) of less than 30, * Affiliated to a social security scheme, * Having read the information document and given in writing their free and informed consent to participate in the study. For healthy volunteers : * Subjects aged 18 to 40, * Having a Body Mass Index (BMI) of less than 30, * Having a Beigthon score \<5 (no joint hypermobility), * Having normal muscle strength, * Affiliated to a social security scheme, * Having read the information document and given in writing their free and informed consent to participate in the study. Exclusion Criteria: For EDS patients : * Subjects under 18, * Proprioceptive physiotherapy (Huber 360 platform type, LPG) in progress or already performed, * previous treatment of hEDS capable of limiting the effects of rehabilitation (e.g. orthodontics, orthoptics), * Diagnosis of other connective tissue abnormalities, * Earlier prescription of compression garments, * Pregnant or lactating women, * Lack of effective contraception during the study period for women * Person under tutorship or curatorship, or deprived of liberty by judicial or administrative decision, * Mental or physical impossibility to agree to participate in the study, * Known allergy to one of the components of compression garments, * Disabling motor impairment, or limiting the performance of motor and psychomotor tests. * Simultaneous participation in another clinical study. For healthy volunteers : * Subjects under 18, * History of vascular, neurological, musculoskeletal or vestibular disorders, * Having orthoptic, orthopedic or orthodontic disorders, * Previous history or progressive disease of vascular, ophthalmological, neurological, musculoskeletal condition, or vestibular condition * Pregnant or lactating women, * Person under tutorship or curatorship, or deprived of liberty by judicial or administrative decision, * Mental or physical impossibility to agree to participate in the study, * Simultaneous participation in another clinical study.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Caen Univerity Hospital

    Caen, France

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