Could tight clothing and dance help EDS patients regain balance?
NCT ID NCT04020107
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested whether wearing compression garments and doing specific physiotherapy exercises could improve balance and quality of life in people with hypermobile Ehlers-Danlos syndrome (hEDS). Forty patients with hEDS were followed for a year, first receiving standard care, then adding compression garments and proprioceptive physiotherapy, and finally doing adapted physical activity including dance and stretching. The main goal was to see if these treatments improved postural control measured on a force platform.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- compression garments and proprioceptive physiotherapy
- What this could lead to
- If it works, this could offer a non-drug approach to improve balance and daily function for people with hypermobile Ehlers-Danlos syndrome.
- What could go wrong
- This was a small, early-stage study with only 40 patients and no control group for the main intervention. Results may not apply to all patients or be long-lasting.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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40 people
The number who actually took part.
- Started
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May 2018
- Finished
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Nov 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 40 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: For EDS patients : * Subjects aged 18 to 40, * SEDh patients newly diagnosed for less than 2 years according to international criteria of 2017, * Having a Body Mass Index (BMI) of less than 30, * Affiliated to a social security scheme, * Having read the information document and given in writing their free and informed consent to participate in the study. For healthy volunteers : * Subjects aged 18 to 40, * Having a Body Mass Index (BMI) of less than 30, * Having a Beigthon score \<5 (no joint hypermobility), * Having normal muscle strength, * Affiliated to a social security scheme, * Having read the information document and given in writing their free and informed consent to participate in the study. Exclusion Criteria: For EDS patients : * Subjects under 18, * Proprioceptive physiotherapy (Huber 360 platform type, LPG) in progress or already performed, * previous treatment of hEDS capable of limiting the effects of rehabilitation (e.g. orthodontics, orthoptics), * Diagnosis of other connective tissue abnormalities, * Earlier prescription of compression garments, * Pregnant or lactating women, * Lack of effective contraception during the study period for women * Person under tutorship or curatorship, or deprived of liberty by judicial or administrative decision, * Mental or physical impossibility to agree to participate in the study, * Known allergy to one of the components of compression garments, * Disabling motor impairment, or limiting the performance of motor and psychomotor tests. * Simultaneous participation in another clinical study. For healthy volunteers : * Subjects under 18, * History of vascular, neurological, musculoskeletal or vestibular disorders, * Having orthoptic, orthopedic or orthodontic disorders, * Previous history or progressive disease of vascular, ophthalmological, neurological, musculoskeletal condition, or vestibular condition * Pregnant or lactating women, * Person under tutorship or curatorship, or deprived of liberty by judicial or administrative decision, * Mental or physical impossibility to agree to participate in the study, * Simultaneous participation in another clinical study.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Caen Univerity Hospital
Caen, France
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Other studies related to the condition(s) this trial covers.