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Which contact lens is best for astigmatism? small study pits two designs Head-to-Head

NCT ID NCT06758089

Symptom relief Sponsor: CooperVision International Limited (CVIL) Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study compared two types of soft toric contact lenses for people with astigmatism. Forty-two participants wore each lens briefly and rated them on comfort, vision, and overall satisfaction. The goal was to see which lens performed better in the short term.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
contact lenses (ocufilcon D and somofilcon A)
What this could lead to
If one lens performs better, it could offer people with astigmatism a more comfortable and clearer vision option.
What could go wrong
This was a small, short-term study with only 42 participants, so results may not apply to everyone. The lenses were worn for just 15 minutes, so long-term benefits are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

42 people

The number who actually took part.

Started

Nov 2024

Finished

Dec 2024

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. They are of legal age and capacity to volunteer. 2. They understand their rights as a research subject and are willing and able to sign a Statement of Informed Consent. 3. They are willing and able to follow the protocol. 4. They currently wear soft contact lenses, or have done so within the past two years. 5. They have ocular astigmatism in both eyes of between 0.75DC and 2.00DC. 6. They have a spherical component: plano to -7.00DS (based on ocular refraction). 7. They are expected to be able to be fitted with the study lenses within the power range available. Exclusion Criteria: 1. They have an ocular disorder, which would normally contra-indicate contact lens wear. 2. They have a systemic disorder, which would normally contra-indicate contact lens wear. 3. They are using any topical medication such as eye drops or ointment. 4. They are aphakic. 5. They have had corneal refractive surgery. 6. They have any corneal distortion resulting from previous hard or rigid lens wear or have keratoconus. 7. They are pregnant or breastfeeding. 8. They have an eye or health condition including an immunosuppressive or infectious disease which would, in the opinion of the investigator, contraindicate contact lens wear or pose a risk to study personnel; or a history of anaphylaxis or severe allergic reaction. 9. They have taken part in any contact lens or care system clinical research within two weeks prior to starting this study.

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Conditions

The condition(s) this trial relates to.

astigmatism

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Astigmatism

Contacts and locations

Locations

  • Eurolens Research

    Manchester, United Kingdom

More trials for these conditions

Other studies related to the condition(s) this trial covers.