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Tooth-Derived graft boosts dental implant success in new study

NCT ID NCT06043037

Disease control Sponsor: Kafrelsheikh University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Sep 04, 2026 · Updated 3 times

Summary

This study tested a new way to place dental implants in the front upper jaw. It combined the socket shield technique (keeping a piece of the natural tooth root) with a graft made from the patient's own tooth. Fifty adults aged 20 to 45 with a tooth that needed removal took part. The goal was to see if this combination improved bone and gum healing around the implant compared to the socket shield technique alone.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
autogenous demineralized dentin graft (ADDG)
What this could lead to
If successful, this approach could improve bone and gum stability around front-tooth implants, potentially reducing implant failure and the need for additional procedures.
What could go wrong
This is a small, completed trial with 50 participants, so results may not apply to everyone. The procedure is specialized and may carry risks like infection or graft failure.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Jul 2023

Finished

Aug 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 40 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * above the age of 18years * presence of non-restorable maxillary anterior tooth * had intact socket walls following tooth extraction * the gingival biotype was thick. Exclusion Criteria: * history of systemic condition * history of using bisphosphonates or other drugs that might impact bone turnover * a history of smoking during the previous five years, * a history of any acute infections at the surgical site, * teeth having root resorptions * massive periodontal destruction * buccally fractured root either vertically or horizontally beneath the alveolar crest.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Dental implant failed Implant site reaction Tooth extraction status nos

Contacts and locations

Locations

  • oral medicine and periodontology outpatient clinic, faculty of dentistry, kafrelsheikh University

    Kafr ash Shaykh, Kafrelsheikh, 214312, Egypt

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