Teen brain study seeks to unlock secrets of social connection and suicide risk
NCT ID NCT07294079
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at how teenage girls at high risk for suicidal thoughts react to social threats, like feeling left out. Researchers want to see if these reactions affect how connected they feel to others day-to-day and their risk for suicidal thoughts over time. One hundred girls aged 12-17 will complete brain tasks, daily smartphone surveys, and follow-up questionnaires for 6 months. The goal is to understand why some teens develop suicidal thoughts and behaviors, which could help prevent them in the future.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2026
- Expected to finish
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Aug 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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12 to 17 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Between ages 12-17 * Reported recurrent suicidal thoughts and behaviors and/or non-suicidal self-injury within the past year. * Medically and neurologically healthy, including no evidence of intellectual disability or serious cognitive impairment that would interfere with task performance * Assigned female at birth * Willing and able to give informed assent * Own an iPhone Exclusion Criteria: * Unable to read or speak English or cognitive impairment preventing ability to complete assessments * Lifetime presence of a neurological or serious medical condition * Lifetime presence of a DSM-5 Autistic Spectrum Disorder * Current DSM-5 Psychotic Disorder or severe Substance Use Disorder * Uncorrected visual disturbance (\<20/40 Snellen visual acuity) * Presence of head injury or congenital neurological anomalies (based on parent report).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Pittsburgh
RECRUITINGPittsburgh, Pennsylvania, 15213, United States
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Other studies related to the condition(s) this trial covers.
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