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Friends helping friends: a novel social-network strategy to boost HIV prevention

NCT ID NCT03823209

Prevention Sponsor: Medical College of Wisconsin Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 30, 2026 · Last updated Jul 31, 2026 · Updated 1 time

Summary

This study tests whether training influential members of social networks to talk about PrEP can encourage more African-American men who have sex with men to use it. Half of the recruited networks will have their leaders trained to share accurate PrEP information and counter misconceptions, while the other half will receive standard brief HIV prevention counseling. The goal is to see if this peer-driven approach increases PrEP uptake and knowledge in underserved cities.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
social network leader training to promote PrEP
What this could lead to
If effective, this approach could boost PrEP use and reduce HIV infections in underserved communities.
What could go wrong
The trial is relatively small and relies on self-reported PrEP use, which may not reflect actual behavior. Results may not generalize to other groups.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

352 people

The number who actually took part.

Started

Jan 2019

Finished

Jun 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 years and older

Sex

Male participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: INDIVIDUALS: 1. Age 16 or older 2. For the seed only, self-report of HIV-negative serostatus or unknown serostatus 3. Except for the seed, being named as a friend by an already-enrolled participant 4. Male at birth 5. Sex with at least one male partner in the past 12 months NETWORKS 1. More than 49% of the seed's eligible friends agree to participate 2. More than 49% of all network members self-report they are HIV-negative at baseline Exclusion Criteria: INDIVIDUALS: 1. Age 15 or younger 2. For the seed only, self-report of HIV-positive serostatus 3. Except for the seed, not being named as a friend by an already-enrolled participant 4. Not male at birth 5. No report of sex with at least one male partner in the past 12 months NETWORKS 1. Less than 50% of the seed's eligible friends agree to participate 2. Less than 50% of all network members self-report they are HIV-negative at baseline

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Conditions

The condition(s) this trial relates to.

AIDS HIV infectious disease prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Human immunodeficiency virus

Contacts and locations

Locations

  • AIDS TaskForce of Greater Cleveland

    Cleveland, Ohio, 44113, United States

  • Medical College of Wisconsin

    Milwaukee, Wisconsin, 53202, United States

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