Can emotion training help those at risk for schizophrenia? new study investigates.
NCT ID NCT04681807
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how young people (ages 15-35) with a parent or sibling who has schizophrenia process social cues like facial expressions. Researchers used brain scans and emotion recognition tests to understand these abilities. They also tested whether a computer-based training program could help improve emotion recognition. The goal was to learn more about early signs of risk and potential ways to help.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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82 people
The number who actually took part.
- Started
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Jul 2021
- Finished
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Aug 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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15 to 35 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Between (or equal to) 15-35 years of age * Ability to read/speak fluent English * Diagnosis of SZ, schizoaffective disorder or schizophreniform confirmed for 1st degree relative by referring psychiatrist or two reliable informants (using the adapted FIGS questionnaire). Exclusion Criteria: * No diagnosis of psychosis related disorder * Significant neurological or medical disorders that may produce cognitive impairment * Current epilepsy or previous history of seizures * Previous head injury with current continuing symptoms (i.e., cognitive ability, dizziness, etc.) * Recent history of substance abuse or dependence (within past 3 months) * MRI contraindication (e.g. metallic head implant, history of seizure, pacemaker, pregnancy, etc.) * Current IQ \< 70 as measured by the Wechsler Abbreviated Scale of Intelligence Scale (WASI)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Royal Ottawa Mental Health Centre
Ottawa, Ontario, K1Z 7K4, Canada
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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