Can you read emotions? study probes social brain in rare movement disorder
NCT ID NCT07099651
First seen Jun 27, 2026 · Last updated Jul 21, 2026 · Updated 2 times
Summary
This study looks at whether people with a rare inherited movement disorder called spinocerebellar ataxia have trouble recognizing emotions or understanding social situations. Researchers will compare 160 patients to healthy volunteers using tests like recognizing facial expressions and interpreting social stories. The goal is to better understand these social challenges, not to test a treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 160 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Dec 2025
- Expected to finish
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Jan 2029
An estimate. End dates often move.
- Lead sponsor
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A government agency
The lead sponsor is a government body.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 100 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: For all participants: * Men or women aged 18 and over * At least 7 years' schooling (CEP level) * Ability to read, write and speak French * Signed informed consent to participate in the study For patients : \- With molecularly confirmed autosomal dominant spinocerebellar ataxia (SCA1, 2, 3, 6, 7, 27B) For controls: \- With no neurological pathology (questioning and neurological examination) Exclusion Criteria: For patients and controls: * Simultaneous participation in another protocol that may interfere with the measurement of the criteria of interest * Physical or cultural factors likely to interfere with test performance * History likely to interfere with cognition (stroke, cranioencephalic trauma, other neurodegenerative disease, epilepsy, learning disability, alcohol dependence syndrome, psychiatric disorders...) * Persons with contraindications to MRI scans * Pregnant, nursing or parturient women * Persons deprived of their liberty by judicial or administrative decision * Persons under compulsory psychiatric care * Persons subject to a legal protection measure * Persons unable to express their consent * Persons not affiliated to or not benefiting from a social security scheme (beneficiary or beneficiary entitled)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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CHU Angers
RECRUITINGAngers, 49933, France