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Scientists probe how smoking alters lung cell messengers

NCT ID NCT03608293

Knowledge-focused Sponsor: Lille Catholic University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at how smoking changes tiny particles called extracellular vesicles found in lung fluid. Researchers will compare samples from 20 smokers and non-smokers to see if these particles affect nearby lung cells. The goal is to find early warning signs of lung disease caused by smoking.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could point toward new biomarkers for early detection of smoking-related lung damage.
What could go wrong
This is a very small, early-stage lab study using cells, not people. Results may not translate to real-world diagnosis or treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

20 people

The number who actually took part.

Started

Jan 2012

Finished

Dec 2013

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * \>18 year-old Exclusion Criteria: * Lack of informed consent * Drug treatment * Professional exposure * Evolutive pregnancy * Bradycardia * Respiratory assistance required, * Diagnosed respiratory distress (e.g. COPD, asthma) * Infectious pneumopathy * Bronchial cancer

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Biomarkers Human bronchial epithelial cells Lung pathogenesis Smokers

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