E-Cigarettes vs. patches: which helps women with cervical dysplasia quit smoking?
NCT ID NCT01989923
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two ways to help women with cervical dysplasia stop smoking: nicotine patches, gum, or lozenges versus electronic cigarettes. Thirty-one women participated for six weeks. The goal was to see if these methods are acceptable and help reduce or stop smoking. It was a small feasibility study, so results are preliminary.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Nicotine replacement therapy (patches, gum, lozenges) and electronic cigarettes
- What this could lead to
- If successful, this could show that e-cigarettes are a viable option to help women with cervical dysplasia quit smoking, potentially reducing their cancer risk.
- What could go wrong
- This is a very small feasibility study with only 31 participants, so results may not apply to everyone. It does not test whether quitting smoking actually prevents cancer, only whether the methods are acceptable.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
-
Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
-
31 people
The number who actually took part.
- Started
-
Jun 2013
- Finished
-
Apr 2017
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
-
18 to 65 years
- Sex
-
Female participants only
- Healthy volunteers
-
Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female * Smokers (defined as those who have smoked at least daily for the last year and who have smoked greater than or equal to 10 or more combustible cigarettes per day during the last year. * Patients with diagnoses of Cervical Dysplasia, Cervical Cancer and Lower Genital Tract Dysplasia and Cancer * Ages 18-65 years Exclusion Criteria: * Patients unwilling to commit to a 6-week intervention that may include either NRT or ENDS. * Patients with previous diagnoses of or treatment for cancer - with the exception of non-melanoma skin cancer. * Presence of any known stroke, heart disease, heart attack, or irregular heart beat. * Pregnancy and lactation. * Plan to continue to use other nicotine in addition to the products supplied by the study. These would include: chewing tobacco, snuff, an additional nicotine patch or other nicotine containing products. * High blood pressure, not well controlled with medication. * Patients using a non-nicotine "smoking cessation medication." * Patients taking a prescription medicine for depression or asthma.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Cervical cancer are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Stephenson Cancer Center
Oklahoma City, Oklahoma, 73104, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can pulsed radiation extend life in metastatic cervical cancer?
- Robotic surgery vs standard approaches: does the platform change cancer outcomes?
- New antibody aims to preserve immune checkpoint while fighting cancer
- Smart speculum could bring cervical cancer screening to remote areas
- Your gut bacteria may hold the key to whether immunotherapy works
- Amazon plant put to the test against Cancer's relentless tiredness