Could secondhand smoke slow a Child's recovery from anesthesia?
NCT ID NCT07831434
First seen Sep 21, 2026 · Last updated Sep 21, 2026
Summary
Researchers are studying whether children exposed to secondhand smoke recover muscle strength more slowly after receiving rocuronium, a muscle relaxant used during general anesthesia for dental work. The study follows children aged 2 to 12 who receive rocuronium as part of routine anesthesia. After the breathing tube is removed, a monitor measures how completely their muscles have recovered. The goal is to see how often incomplete muscle recovery occurs and whether it is more common in children who live around smokers.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If a link appears, it could help anesthesiologists tailor monitoring and dosing for children who live with smokers.
- What could go wrong
- This is a small observational study, so it can show a pattern but not prove cause and effect. Parent-reported smoke exposure may be inaccurate, and other factors could explain any difference.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
About 55 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
-
Sep 2026
An estimate. Start dates often move.
- Expected to finish
-
Sep 2027
An estimate. End dates often move.
- Lead sponsor
-
Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will consist of children aged 2-12 years undergoing dental procedures under general anesthesia with rocuronium administration. Participants will be categorized according to the presence or absence of passive smoke exposure as reported by a parent or legal guardian. Postoperative neuromuscular function will be assessed using quantitative train-of-four monitoring after extubation.
- Ages
-
2 to 12 years
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Children aged 2-12 years * Scheduled to undergo dental procedures under general anesthesia * Administration of rocuronium as part of routine anesthetic management * Written informed consent obtained from a parent or legal guardian Exclusion Criteria: * Known neuromuscular disease * Known allergy or contraindication to rocuronium * Use of medications known to significantly affect neuromuscular transmission * Severe hepatic or renal dysfunction * Inability to obtain reliable postoperative TOF measurements
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Neuromuscular block prolonged are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
-
The places running it
1 site. The list below names each one and where it is.
-
The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
-
A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
-
Istanbul University-Cerrahpasa, Institute of Cardiology
Istanbul, Istanbul, 34093, Turkey (Türkiye)