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Breathe easy: App-Guided exercise may lower blood pressure

NCT ID NCT06229873

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether a smartphone app can guide people through a simple breathing exercise to lower systolic blood pressure. 33 adults with elevated blood pressure did 5 minutes of breathing training daily for 6 weeks, either guided by an app or by researchers in a clinic. The goal was to see if the app-based approach works as well as the clinic-based one.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
inspiratory muscle strength training (IMST) device
What this could lead to
If it works, this could offer a simple, drug-free way to help lower blood pressure at home.
What could go wrong
This is a small, early study with only 33 participants. It compares app-guided training to clinic-based training, so results may not apply to everyone. The long-term effects are unknown.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

33 people

The number who actually took part.

Started

Jun 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age 18+ years * Ability to provide informed consent * Willing to accept random assignment to condition * Systolic blood pressure 120-160 mmHg * Owns an Apple or Android smartphone * Body mass index \<40 kg/m2 * Subject report of being weight stable in the prior 3 months (\<2 kg weight change) and willing to remain weight stable during the 6-week intervention period * Subjects taking antihypertensive medications will be included provided they meet the other inclusion criteria, including systolic blood pressure. Medication regimen (prescription and dosing) must be stable for at least 3 months prior to enrollment in the study and must remain stable during the 6-week intervention period. These medications will not be withheld prior to experimental protocols. * If woman of childbearing age: * Not pregnant (defined as self-report of pregnancy) * Willing to be abstinent or use approved contraception (i.e., hormonal contraception, intrauterine devices, barrier methods such as condoms with spermicide, and surgical sterilization) throughout the duration of the study Exclusion Criteria: * Age \<18 years * Participant report of a chronic overt medical condition (e.g., unstable cardiovascular disease, recent myocardial infarction or stroke, cancer) that may make it unsafe to participate in the study under the discretion of the study Medical Director. * Inability to abstain from consumption of alcohol for 12 hours on experimental days. * Report of blood donation within 8 weeks prior to enrolling in the study or unwillingness to abstain from donating blood for 8 weeks after completing the study * Participant report of current ruptured eardrum or any other current condition of the ear * Participant report of recent abdominal surgery (past 3 months) or current abdominal hernia * Participant report of current asthma with very low symptom perception, frequent and severe exacerbations, or abnormally low perception of dyspnea * Participant report of past or current costochondritis (inflammation of the cartilage that joins the ribs to the breastbone)

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Conditions

The condition(s) this trial relates to.

hypertensive disorder Treatment Adherence and Compliance

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Colorado Boulder

    Boulder, Colorado, 80309, United States

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