Den här översättningen är inte klar ännu. Den här sidan är just nu på engelska.

Gå till den engelska sidan

Can a smartwatch help control a common heart rhythm problem?

NCT ID NCT07445789

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study compares two common heart rate-lowering drugs, verapamil and metoprolol, in 436 adults with paroxysmal atrial fibrillation (AF). It also tests whether using a smartwatch for self-care can reduce hospital visits and improve symptoms. The goal is to find better ways to manage AF and avoid emergency care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
verapamil or metoprolol
What this could lead to
If successful, this could show that verapamil or smartwatch-guided self-care reduces hospital visits and improves quality of life for people with paroxysmal atrial fibrillation.
What could go wrong
This is a phase 4 trial, so both drugs are already approved, but results may not apply to all AF patients. The smartwatch component depends on patient engagement and may not show clear benefits.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Participants

About 436 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Jun 2026

An estimate. Start dates often move.

Expected to finish

Jun 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

7.2 Inclusion criteria In order to be eligible to participate in this study, a subject must meet all of the following criteria: * Age ≥ 18 years old * ECG documented diagnosis of paroxysmal AF * Presence of symptomatic paroxysmal AF, defined as recurrent self-terminating AF (≥ 2 episodes in last 4 months) documented by typical symptoms, ECG or photoplethysmo-gram * Able and willing to sign informed consent. For SMART sub study only: \- Own a smartphone 7.3 Exclusion criteria A potential subject who meets any of the following criteria will be excluded from participation in this study: * A history of electrical cardioversion for persistent AF * History of AF episode \> 7 days * Previous or current chronic amiodaron use. * A history of pulmonary vein ablation * Taking part in another randomized trial * Reduced life-expectancy of \< 1 year * Presence of contra-indication for verapamil or metoprolol * Pregnant or breastfeeding women. Or women who are planning to become pregnant during the study period. * For substudy patients: already participating in an eHealth program Contraindications for verapamil or metoprolol: * Known hypersensitivity, intolerance or allergy to verapamil, metoprolol, or any excipi-ents. * Current use of verapamil, diltiazem, beta-blockers or digoxin, or \< 5 half-lives ago at the time of randomization. * Concomitant use of medications with absolute contraindications for verapamil or metoprolol (e.g., strong CYP3A4 inhibitors).\* * Resting heart rate \< 50 beats per minute at baseline. * Symptomatic hypotension (or systolic blood pressure \< 100 mmHg). * Second- or third-degree atrioventricular block. * Sick sinus syndrome or sinus node disease. * Wolff-Parkinson-White syndrome. * Severe heart failure (NYHA class III-IV or left ventricular ejection fraction \< 45%). * Clinically significant constipation requiring medical intervention. * Severe bronchial asthma or COPD with bronchial hyperreactivity. * Untreated pheochromocytoma (unless patient is concomitantly treated with an α-blocker). * Type 1 diabetes mellitus with frequent symptomatic hypoglycaemia where β-blocker use would pose unacceptable risk due to masking of symptoms. * Severe symptomatic peripheral arterial disease or disabling Raynaud's phenomenon. * Pacemaker therapy in place. An implanted loop recorder is not a contraindication. * Severe hepatic impairment (Child-Pugh class C). * Severe renal impairment (eGFR \< 30 ml/min/1.73m²). \*Patients using statins can be switched to an equivalent dose of rosuvastatin prior to ran-domization. Patients using oral anticoagulation need to be switched to apixaban or rivaroxa-ban.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Atrial fibrillation (AF) are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  2. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

More trials for these conditions

Other studies related to the condition(s) this trial covers.