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New cocktail aims to boost chemo power against aggressive lymphoma

NCT ID NCT04978584

First seen Nov 01, 2025 · Last updated Jun 18, 2026 · Updated 33 times

Summary

This study tests whether giving a mix of targeted drugs (rituximab, lenalidomide, acalabrutinib, tafasitamab) before and with standard chemotherapy can better control a fast-growing type of lymphoma called DLBCL. About 62 adults with newly diagnosed disease will participate. The goal is to see if this approach improves tumor shrinkage and complete response rates.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

diffuse large B-cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.