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Could a simpler lymph node check replace major surgery for endometrial cancer?

NCT ID NCT04276532

First seen May 15, 2026 · Last updated Jun 18, 2026 · Updated 3 times

Summary

This study compares two surgical approaches for women with middle-to-high risk endometrial cancer that hasn't spread beyond the uterus. One group gets sentinel lymph node sampling (removing only a few key nodes), while the other gets standard pelvic lymphadenectomy (removing many nodes). The goal is to see if the less invasive method is just as good at preventing cancer from coming back, while causing fewer side effects. About 780 women are taking part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Tenth People's Hospital Affiliated to Tongji University

    Shanghai, Shanghai Municipality, 200072, China

Conditions

The condition(s) this trial relates to.

endometrial cancer endometrial carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.