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Losing sleep? your hormones may be out of whack

NCT ID NCT03142893

First seen Oct 31, 2025 · Last updated Jun 23, 2026 · Updated 30 times

Summary

This study looks at how not getting enough sleep changes key hormones in healthy men aged 22 to 45. Researchers will measure stress hormones like cortisol and sex hormones like testosterone after several nights of restricted sleep. The goal is to better understand the body's hormonal response to sleep loss, which could help explain related health issues.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Los Angeles Biomedical Research Institute

    Torrance, California, 90509, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Ketoconazole, Ganirelix, Dexamethasone, Cosyntropin, Recombinant Human Luteinizing Hormone

What this could lead to

If successful, this study could help explain why sleep loss affects hormones like cortisol and testosterone, potentially pointing toward ways to reduce related health risks.

What could go wrong

This is a small, early-phase study in healthy men only, so results may not apply to women or people with health conditions. It is designed to understand mechanisms, not to test a treatment.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.